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New theory over mystery death of Botticelli's Birth of Venus model, Simonetta Vespucci

eurekalert.org

A new medical theory links Simonetta Vespucci's mysterious death at 23 to a pituitary tumor — and suggests the iconic squint in Botticelli's Venus was a symptom, not a style choice.

RetrodiagnosisPathological Art AnalysisNeuroendocrine TheoryMedical History
New theory over mystery death of Botticelli's Birth of Venus model, Simonetta Vespucci

Theory Briefing

  • Simonetta Vespucci, the model for Botticelli's Birth of Venus, died at just 23 — long attributed to tuberculosis but now re-examined.
  • Researchers propose a pituitary adenoma caused her premature death, linking a brain tumor to one of art history's greatest mysteries.
  • The Venus figure's famous squint, long admired as an artistic detail, may actually reflect a real neurological symptom of Vespucci's tumor.